Premarin Vaginal Cream (Conjugated Estrogens)

Premarin Vaginal Cream (Conjugated Estrogens) used

Premarin Vaginal Cream (Conjugated Estrogens) is used to treat menopausal changes in and around the vagina, caused by a lack of oestrogen production by the ovaries. Premarin Vaginal Cream (Conjugated Estrogens) is a short-term hormone replacement therapy (HRT) used to treat atrophic vaginitis (also called vaginal atrophy), which occurs when tissues in and around the vagina become thinner and less elastic and produce less lubrication, causing symptoms of dryness burning and itching around the vagina, which can also lead to inflammation in the vaginal tissues. Changes in the skin of the vagina can lead to sex being uncomfortable or painful, and to an increased susceptibility to vaginal or urinary infections, also mild urinary incontinence. Premarin Vaginal Cream (Conjugated Estrogens) provides a topical oestrogen treatment that helps to restore the vaginal tissue, by treating the underlying cause, which reduces symptoms and prevents recurrent infections.

Premarin Vaginal Cream (Conjugated Estrogens) work

Premarin Vaginal Cream (Conjugated Estrogens) contains conjugated oestrogens, which is a mixture of natural oestrogens isolated exclusively from natural sources. Oestrogen is a steroid hormone produced by the ovaries that binds to specific receptors inside oestrogen-responsive cells and stimulates them to make proteins involved in producing secondary sexual characteristics, including thickening of the vaginal wall and increasing vaginal secretion. When Premarin Vaginal Cream (Conjugated Estrogens) is inserted into the vagina, oestrogen is slowly released and absorbed into the vaginal skin layer where it reverses changes in the vagina by stimulating thickening of the skin, reducing inflammation and restoring the physiological pH and normal microflora (the “good” bacteria that normally live in the skin and increases resistance to infection with other bacteria that cause vaginal or urinary infections). The restoring effect of Premarin Vaginal Cream (Conjugated Estrogens) reduces symptoms of atrophic vaginitis which can be maintained with continued use.