Apo-Nadolol (Nadolol Tablets)

Apo-Nadolol (Nadolol Tablets) used

Apo-Nadolol (Nadolol Tablets) are used to treat a variety of conditions of the cardiovascular system. These include, control of mild to moderate hypertension (high blood pressure), alone as monotherapy or in combination with other antihypertensive agents, especially thiazide diuretics, to lower blood pressure and reduce the risk of complications such as stroke and heart attack. Apo-Nadolol (Nadolol Tablets) are also used for long-term management of angina (chest pain) in patients with heart disease; and control of most forms of arrhythmias (rapid or irregular heart beat). There is also some evidence that using Apo-Nadolol (Nadolol Tablets) long-term may help in the prevention of myocardial infarction (heart attack) and treatment of heart failure to improve survival and quality of life. Apo-Nadolol (Nadolol Tablets) are also used for preventing migraine, and to treat symptoms of hyperthyroidism (overactive thyroid) as well as preparing patients for thyroid surgery. Apo-Nadolol (Nadolol Tablets) work through a common mechanism in several different body systems to manage the condition and relieve symptoms by reducing heart rate (pulse), workload on the heart (force needed to pump) and oxygen demand by the heart, which increases blood flow and lowers blood pressure.

Apo-Nadolol (Nadolol Tablets) work

Apo-Nadolol (Nadolol Tablets) contain nadolol, a non-selective beta-blocker (also known as beta adrenergic antagonist), that binds to beta receptors found in vascular smooth muscle of blood vessel walls and several organs of the body, including the heart and lungs. Nadolol in Apo-Nadolol (Nadolol Tablets) blocks the action of chemicals called catecholamines, such as adrenaline (epinephrine) and noradrenaline (nor epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline works binds to beta-receptors in the heart to stimulate increased heart rate and constriction (narrowing) of blood vessels. These actions of adrenaline are reduced or inhibited by nadolol in Apo-Nadolol (Nadolol Tablets), to slow heart rate, dilate (widen) blood vessels, lower blood pressure, and increase blood flow and oxygen to the heart. When the heart beats more slowly and with less force, this reduces the pain associated with angina and frequency of angina attacks, also helps the heart beat to become more regular and reduces the force needed to pump blood around the body, which helps lower blood pressure. Since beta-receptors are found in many tissues, all short-term and long-term symptom relief due to taking Apo-Nadolol (Nadolol Tablets), is based on blocking beta-receptors in the target tissue, for example, reducing symptoms associated with hyperthyroidism (overactive thyroid), including rapid heart rate, sweating and tremor. Although the mechanism by which Apo-Nadolol (Nadolol Tablets) help prevent migraine is not fully known, it is thought to involve prevention of vasoconstriction (blood vessel narrowing) of the internal carotid artery, by blocking beta receptors in the brain and prevention of excessive adrenergic vasodilation in the external carotid artery, which happens during a migraine attack. Apo-Nadolol (Nadolol Tablets) are formulated for controlled release so that nadolol is that released in a sustained and time controlled manner, to ensure a more even effect over 24 hours, which provides better symptom relief with fewer side effects.